Histological study of bone quality in the implant sites prepared by the drilling and expansion techniques
Introduction: Bone drilling and expansion techniques have been used for implant site preparation. However, histological studies comparing these two techniques are limited. This study aimed to histologically assess the bone quality in the implant sites prepared by the bone drilling and expansion techniques in a sheep model.
Materials and Methods: This experimental animal study was conducted on three sheep and four sites were chosen in their mandibles. Implant holes were created by bone drilling and expansion techniques in an alternate fashion. The first sheep underwent vital perfusion immediately after surgery and its mandible was fixed. The second and the third sheep were subjected to vital perfusion 19 and 26 days after surgery, respectively. The collected samples were stained with hematoxylin and eosin and the percentage of osteogenesis, the amount of ossification and sequester area, were measured by computer assisted histomorphometric analysis system. The amount of inflammation was estimated for each sample, considering the frequency of inflammatory cells infiltration, in terms of degree of inflammation as zero, less than 10% and more than 10%, under x400 magnification.
Results: No significant difference was noted between the drilling and expansion techniques for implant site preparation in terms of degree of inflammation or rate of osteogenesis. The amount of sequesters was different between the two groups in the first days after surgery but no significant difference was noted in this regard between the two groups after 3 weeks.
Conclusion: according to the histological evaluation, the method of implant sites preparation does not effect of quality of bone regeneration.
A signature of author below certifies compliance with the following statements:
Copyright transfer; in signing this Agreement:
1. I hereby warrant that this article is an original work, has not been published before and is not being considered for publication elsewhere in its final form either in printed or electronic form;
2. I hereby warrant that you have obtained permission from the copyright holder to reproduce in the Article (in all media including print and electronic form) material not owned by you, and that you have acknowledged the source;
3. I hereby warrant that this article contains no violation of any existing copyright, moral rights or other third party right or any material of an obscene, indecent, defamatory or otherwise unlawful nature and that to the best of your knowledge this Article does not infringe the rights of others;
4. I hereby warrant that in the case of a multi-authored Article you have obtained, in writing, authorization to enter into this Agreement on their behalf and that all co-authors have read and agreed the terms of this agreement;
5. I warrant that any formula or dosage given is accurate and will not if properly followed injure any person;
6. I have made a significant scientific contribution to the study and I have read the complete manuscript and take responsibility for the content and completeness of the final surmised manuscript;
7. I will indemnify and keep indemnified the Editors, the Regeneration, Reconstruction and Restoration journal's editor against all claims and expenses (including legal costs and expenses) arising from any breach of this warranty and the other warranties on your behalf in this Agreement.
Conflict of interest disclosure
All institutional or corporeal affixations of mine and all funding sources for the study are acknowledged. I certify that I have no commercial association that might represent a conflict of interest in connection with the submitted manuscript.
The names and email addresses entered in this journal site will be used exclusively for the stated purposes of this journal and will not be made available for any other purpose or to any other party.