Photobiomodulation as a Coadjutant in Management of Trigeminal Neuralgia: A Case Series Study and Review of the Literature
Journal of "Regeneration, Reconstruction & Restoration" (Triple R),
Vol. 9 (2024),
18 March 2024,
https://doi.org/10.22037/rrr.v9.38696
Background and objectives: Trigeminal Neuralgia (TN) is a disabling neuropathic pain that can severely compromise the quality of life the patient. The current standard treatments for TN lack enough safety and efficacy; therefore, utilizing new remedies is mandatory. Photobiomodulation (PBM) is a novel treatment suggested for neuropathic pain, but we need more studies on using low-level laser to manage TN.
Materials and methods: 7 cases of primary confirmed TN were enrolled in this study. Diode laser (InGaAs) was utilized with 980 nm wavelength to irradiate the involved painful areas and trigger zones. Painful areas were irradiated intra and extraoral with the duration of 20 seconds and in osculation condition in continual wave (CW). The energy density of intra and extraoral irradiation was 4 j/cm2 and 6 j/cm2 respectively. Duration of treatment was about 3 weeks. VAS (Visual analogue scale) score was used as an outcome measure before and after treatment. Prior to enrollment, the VAS of self-reported pain of subjects was 10.
Results: VAS scores gradually decreased from the 4th session in all patients, as far as following 15th session. VAS scores in all patients were 1-2 degree at the end of third week of study. Along with PBM therapy, the dose of carbamazepine for pain management was reduced until the pain intensity was so low that it was not needed.
Conclusion: It seems that the PBM could be employed as adjuvant therapy for TN, but further study with precise laser dosing and more outcome measures are needed to apply this technology confidently.